Cestrum nocturnum Flower Extracts Attenuate Proliferation and Induce Apoptosis in Malignant Cells through Inducing DNA Damage and Inhibiting Topoisomerase II Activity

Table 1

The concentrations of the CN flower fractions, which induced 50% decrease in malignant cells survival, according to MTT assay.

Fractions	IC50 (μg/mL)
	CNE-2Z	Bel-7404	HeLa
B1	411.71	440.11	845.9
B2	213.51	281.01	933.58
B3	34.42	37.23	73.87
B4	17.50	11.08	23.59
B5	202.1	201.13	181.70
C1	130.33	75.9	150.78
C2	162.53	109.49	909.41
C3	403.13	205.30	550.77
C4	19.78	18.71	19.21
C5	22.98	19.62	19.70
C6	211.10	360.32	144.68
C7	588.06	222.92	211.01
C8	387.63	113.80	335.91
C9	245.55	109.38	199.93
C10	272.11	201.4	452.3
5-Fu	16.43	2.32	8.96

The cells were exposed to the agents for 72 h.