Allium stipitatum Extract Exhibits In Vivo Antibacterial Activity against Methicillin-Resistant Staphylococcus aureus and Accelerates Burn Wound Healing in a Full-Thickness Murine Burn Model

Figure 4

Representative photomicrographs of burn wound (uninfected treated) healing in different treatment groups. Skin sections showing an area of (a) mice with burn wound (normal control) showing epidermal ulceration (EU) made up of necrotic tissue debris and blood clot and diffuse leucocytic infiltration in the dermis (LI) at day 5 after burn, H&E ×100, (b) BW + 1% SSD, (h) BW + 5% ASHE, and (i) BW + 5% ASDE, all showing presence of epidermal epithelialization (E) with fibroblast proliferation (F) in the dermis at day 15 after burn, H&E ×400, (c) BW + 1% SSD, (d) BW + 2% ASHE, (e) BW + 2% ASDE, (f) BW + 1% ASHE, and (g) BW + 1% ASDE showing complete epidermal epithelialization (E) with presence of keratin proliferation, and fibroblast proliferation (F) in the dermis (D) at 20 days after burn and treatment, H&E ×400. Note the absence of exocrine glands and hair follicles in the dermis (D).