Allium stipitatum Extract Exhibits In Vivo Antibacterial Activity against Methicillin-Resistant Staphylococcus aureus and Accelerates Burn Wound Healing in a Full-Thickness Murine Burn Model

Table 3

Histological lesion score in mice skin tissue with various treatments examined at day 20.

Group/treatment	C	ED	PMN	MNC	U	D & N	NV	FP	EP
BW only
BW + SOB
BW + MRSA
BW + MRSA + SOB
BW + SSD (1%)
BW + MRSA + SSD (1%)
BW + MRSA + ASHE (1%)
BW + MRSA + ASHE (2%)
BW + MRSA + ASHE (5%)
BW + ASHE (1%)
BW + ASHE (2%)
BW + ASHE (5%)
BW + MRSA + ASDE (1%)
BW + MRSA + ASDE (2%)
BW + MRSA + ASDE (5%)
BW + ASDE (1%)
BW + ASDE (2%)
BW + ASDE (5%)

Superscripts with different letters in a column are significantly different at . Values are expressed as mean ± SEM (0: no lesion distribution; 1: mild distribution; 2: moderate distribution; and 3: marked distribution).
BW: burn wound; SOB: simple ointment base; MRSA: methicillin-resistant S. aureus; SSD: silver sulfadiazine; ASHE: A. stipitatum hexane extract; ASDE: A. stipitatum dichloromethane extract; C: congestion; ED: edema; PMN: polymorphonuclear cells; MNC: mononuclear cells; U: ulceration; D & N: degeneration and necrosis; NV: neovascularization; FP: fibroblast proliferation; EP: epithelialization. Values are presented as the average of one unit square, that is, 2 × 2 mm² area of tissue with lesions.