| | Univariate | Multivariate | | OR | 95% CI | OR | 95% CI |
| Age (continuous) | 1.01 | (0.99, 1.03) | | | Sex, male (ref. female) | 0.97 | (0.67, 1.37) | | | Disc degeneration grade (ref. I) | II | 3.39 | (0.37, 31.38) | | | III | 3.14 | (0.36, 27.38) | | | IV | 4.57 | (0.53, 39.77) | | | V | 16.67 | (1.36, 204.03) | | | Disc herniation type (ref. protrusion) | Bulging | — | | | | Extrusion | 4.66 | (2.15, 10.13) | 2.49 | (1.10, 5.60) | Migration | 11.82 | (5.02, 27.85) | 6.3 | (2.58, 15.42) | Sequestration | 12.190 | (3.91, 37.95) | 3 | (0.84, 10.68) | Komori migration classification (ref. 1) | 2 | 2.48 | (1.58, 3.89) | 1.7 | (1.04, 2.76) | 3 | 5.46 | (3.24, 9.18) | 2.46 | (1.37, 4.42) | Modic change type of vertebral body (ref. 0) | 1 | 0.84 | (0.30, 2.37) | | | 2 | 4.4 | (0.94, 2.10) | | | 3 | 0.7 | (0.06, 7.81) | | | Modic change of vertebral body area (ref. none) | Above the herniated disc | 0.94 | (0.37, 2.35) | | | Below the herniated disc | 1.410 | (0.57, 3.46) | | | Both above and below the herniated disc | 1.38 | (0.90, 2.12) | | | Time interval between MRIs (continuous) | 1 | (0.99, 1.00) | | | Total treatment duration (continuous) | 1 | (0.99, 1.00) | | |
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