Research Article
Influences of Realgar-Indigo naturalis, A Traditional Chinese Medicine Formula, on the Main CYP450 Activities in Rats Using a Cocktail Method
Table 3
Recovery of the developed assay (
).
| Number | QC conc. (μg⋅ml−1) | Recovery (Mean ± S.D.) | RSD (%) |
| Caffeine | 5.38 | 96.71 ± 3.05 | 3.15 | 10.75 | 91.04 ± 2.16 | 2.38 | 51.80 | 93.64 ± 5.54 | 5.92 |
| Chlorzoxazone | 10.16 | 99.18 ± 2.47 | 2.49 | 20.32 | 97.91 ± 3.41 | 3.49 | 101.60 | 94.98 ± 2.00 | 2.11 |
| Tolbutamide | 11.13 | 90.04 ± 3.80 | 4.22 | 22.26 | 90.81 ± 2.88 | 3.18 | 109.60 | 85.65 ± 2.26 | 2.64 |
| Midazolam | 11.01 | 90.95 ± 4.25 | 4.67 | 22.02 | 90.41 ± 1.95 | 2.16 | 105.30 | 95.27 ± 9.10 | 9.55 |
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