Roles of Nitric Oxide and Prostaglandins in the Sustained Antihypertensive Effects of Acanthospermum hispidum DC. on Ovariectomized Rats with Renovascular Hypertension
Effects of oral administration of purified aqueous extract obtained from A. hispidum DC. (ESAH) on urinary volume and electrolyte excretion, pH, and density on 1st day of treatment.
(ml/100 g/8 h)
ESAH (30 mg/kg)
ESAH (100 mg/kg)
ESAH (300 mg/kg)
Values are expressed as mean ± SEM of 6-7 rats in each group in comparison with the positive control (C+; ) or Sham-operated group () using one-way ANOVA followed by Dunnett’s test. El: excreted load; HCTZ: hydrochlorothiazide; ENAL: enalapril.
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