Schisandrae Fructus Reduces Symptoms of 4-Vinylcyclohexene Diepoxide-Induced Ovarian Failure in Mice
Table 1
Time course of changes in tail skin temperature of mice.
Tail skin temperature
1 weeks
3 weeks
5 weeks
7 weeks
9 weeks
CON
22.64 ± 0.22
22.16 ± 0.08
22.42 ± 0.17
22.34 ± 0.44
23.00 ± 0.13
VCD + Vehicle
22.80 ± 0.08
23.23 ± 0.08
23.63 ± 0.16
23.42 ± 0.19
23.27 ± 0.17
VCD + E2
22.25 ± 0.10
22.98 ± 0.20
22.45 ± 0.15
22.57 ± 0.27#
22.75 ± 0.41
VCD + SF 25 mg/kg
21.94 ± 0.25
21.66 ± 0.20
21.91 ± 0.19
22.79 ± 0.36
22.36 ± 0.27#
VCD + SF 100 mg/kg
21.80 ± 0.20
21.52 ± 0.28
22.64 ± 0.18
21.91 ± 0.27
22.09 ± 0.27
VCD + SF 400 mg/kg
21.60 ± 0.37
21.63 ± 0.31
21.28 ± 0.24
21.55 ± 0.16
23.00 ± 0.35
The tail skin temperature was measured at nine weeks. Data represent mean ± SEM. , compared with the CON group. , , and compared with the VCD + Vehicle group. Group and treatment differences were analyzed via one-way ANOVA with Tukey post hoc analysis.
