Research Article
Apigenin Attenuates Adriamycin-Induced Cardiomyocyte Apoptosis via the PI3K/AKT/mTOR Pathway
Figure 4
Effect of apigenin on the PI3K/AKT/mTOR pathway in hearts from ADR-treated mice. (a) Representative pictures of PI3K-p85, p-AKT, AKT, p-mTOR, and mTOR expression. GAPDH served as the loading control; per group. (b) Quantitative analysis of the PI3K-p85/GAPDH ratio; expression levels were quantified via densitometry and normalized to the expression of GAPDH, which was used as a loading control; per group. (c) Quantitative analysis of the p-AKT/AKT ratio; GAPDH served as the loading control; per group. (d) Quantitative analysis of the p-mTOR/mTOR ratio; per group. GAPDH served as the loading control. Values are presented as the mean ± SEM. compared with the control group; compared with the ADR model group.
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