Improved Lipid Profile Associated with Daily Consumption of Tri-Sura-Phon in Healthy Overweight Volunteers: An Open-Label, Randomized Controlled Trial
Table 2
Effect of Tri-Sura-Phon tea drinking on body mass index, serum lipid profile, glucose and insulin levels, and liver function of healthy overweight volunteers.
Parameters
Tested group
Mean (SD)
Baseline
4th week
8th week
BMI (kg/m2)
Tri-Sura-Phon
27.7 (4.5)
27.6 (4.5)
27.6 (4.5)
Placebo
28.3 (4.0)
28.0 (4.2)
28.2 (4.1)
Total cholesterol (mg/dL)
Tri-Sura-Phon
223.7 (37.6)
213.5 (29.2)
201.3 (36.2)
Placebo
210.5 (33.0)
213.6 (37.2)
211.9 (42.6)
Triglycerides (mg/dL)
Tri-Sura-Phon
147.5 (74.3)3
79.3 (24.2)
103.4 (40.2)
Placebo
142.4 (75.9)
125.6 (61.5)
96.1 (37.5)
Low density lipoprotein (mg/dL)
Tri-Sura-Phon
130.5 (40.5)
129.7 (30.6)
108.5 (37.6)
Placebo
116.2 (35.5)
125.0 (33.7)
131.7 (44.0)
High density lipoprotein (mg/dL)
Tri-Sura-Phon
63.4 (12.8)
68.0 (14.1)3
72.4 (13.4)
Placebo
65.8 (10.0)
67.6 (11.4)
60.9 (13.6)
FBG (mg/dL)
Tri-Sura-Phon
76.2 (6.1)1,2,3
84.1 (7.9)
84.3 (8.4)
Placebo
81.5 (12.0)
91.4 (12.8)
91.2 (9.0)
Insulin level (uU/mL)
Tri-Sura-Phon
8.9 (4.1)
8.3 (3.5)3
9.9 (5.0)
Placebo
10.9 (7.0)
8.7 (4.2)
10.9 (7.0)
Albumin (gm/dL)
Tri-Sura-Phon
4.6 (0.5)2
4.5 (0.5)2
4.1 (0.5)
Placebo
4.5 (0.5)
4.1 (0.4)
4.6 (0.5)
Total bilirubin (mg/dL)
Tri-Sura-Phon
0.7 (0.4)
0.9 (0.3)3
0.8 (0.4)
Placebo
0.8 (0.5)
0.9 (0.4)
0.6 (0.5)
Direct bilirubin (mg/dL)
Tri-Sura-Phon
0.0 (0.0)
0.0 (0.0)
0.0 (0.0)
Placebo
0.0 (0.2)
0.0 (0.0)
0.0 (0.0)
AST (U/L)
Tri-Sura-Phon
20.1 (5.6)2,3
22.6 (6.8)
19.8 (4.3)2,3
Placebo
22.7 (7.1)
24.2 (5.1)
24.3 (13.2)
ALT (U/L)
Tri-Sura-Phon
21.1 (14.0)3
20.8 (13.4)3
18.7 (13.5)3
Placebo
22.5 (11.6)
20.7 (11.1)
30.5 (26.5)
ALP (U/L)
Tri-Sura-Phon
78.1 (20.1)
76.0 (19.5)
69.6 (21.3)
Placebo
77.5 (15.7)
74.8 (18.3)
74.5 (17.0)
GGT (U/L)
Tri-Sura-Phon
25.0 (15.7)
25.7 (16.0)
25.1 (17.7)
Placebo
25.5 (8.6)
23.0 (8.3)
26.0 (12.2)
Uppercase superscript letters indicate the significant differences in parameters between the baseline and week 4 (A) or the baseline and week 8 (B) or weeks 4 and 8 (C) within the treatment. Superscript numbers indicate the significant differences between the parameters at baseline (1), week 4 (2), or week 8 (3) among the treatments. BMI = body mass index, FBG = fasting blood glucose, AST = aspartate aminotransferase, ALT = alanine aminotransferase, ALP = alkaline phosphatase, and GGT = gamma-glutamyl transpeptidase.