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Evidence-Based Complementary and Alternative Medicine
Volume 2017, Article ID 2749643, 8 pages
Research Article

Rapid Screening of Potential Phosphodiesterase Inhibitors from the Roots of Ilex pubescens Hook. et Arn. Using a Combination of Ultrafiltration and LC–MS

1Guangzhou Key Laboratory of Chinese Medicine Prevention and Treatment of Chronic Heart Failure, The First Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510407, China
2Department of Pharmaceutical Sciences, University of Tennessee Health Science Center, Memphis, TN 28163, USA
3School of Pharmaceutical Sciences, Peking University, Beijing 100191, China

Correspondence should be addressed to Shaoxiang Xian; moc.liamtoh@xgnaixoahs

Received 22 November 2016; Revised 15 February 2017; Accepted 12 March 2017; Published 23 March 2017

Academic Editor: Hyunsu Bae

Copyright © 2017 Zichen Liu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

The retention times and MS data of the extract, ultrafiltrate and standard compound were summarized (Table S1). The EIC chromatograms of each compound in negative ion mode of the extract, ultrafiltrate, and blank sample were shown (Figures S1–9).

  1. Supplementary Material