Table 3: KEGG pathways related to sex hormones and lipolysis, significantly enriched (adjusted -value of ≤0.05) by predicted targets of Coicis Semen.

RankKEGG pathwayAdjusted-
value
Genes (targets)

5/63hsa04923:
Regulation of lipolysis
in adipocytes
Beta-1 adrenergic receptor; beta-2 adrenergic receptor; prostaglandin G/H synthase 2; mRNA of PKA catalytic subunit C-alpha; prostaglandin G/H synthase 1

39/63hsa04914:
Progesterone-mediated
oocyte maturation
Cell division protein kinase 2; progesterone receptor; mRNA of PKA catalytic subunit C-alpha

40/63hsa04915:
Estrogen signaling pathway
Nitric oxide synthase; mRNA of PKA catalytic subunit C-alpha; estrogen receptor

48/63hsa04921:
Oxytocin signaling pathway
Nitric oxide synthase; mRNA of PKA catalytic subunit C-alpha; prostaglandin G/H synthase 2