Research Article

Antihyperglycemic, Antidiabetic, and Antioxidant Effects of Garcinia pedunculata in Rats

Table 4

The effects of GP fruit extract and glibenclamide on liver function in normal and STZ-induced diabetic rats.

GroupsLiver function markers
ALT (U/L)AST (U/L)ALP (U/L)LDH (U/L)GGT (U/L)Total bilirubin (mg/dL)Total
protein (g/L)
Albumin (g/L)Globulin (g/L)A/G ratio

Normal Control
Diabetic Control
Diabetic + Glibenclamide
Diabetic + GP (250 mg/kg)
Diabetic + GP (500 mg/kg)
Diabetic + GP (1000 mg/kg)

Data are represented as the mean ± SD (). denotes a significant difference () between the treatment groups and the diabetic control group; denotes a significant difference () when the normal control group was compared to the diabetic control group. The comparisons were made by one-way ANOVA followed by Dunnett’s multiple comparison test.