Compound Wumei Powder Inhibits the Invasion and Metastasis of Gastric Cancer via Cox-2/PGE2-PI3K/AKT/GSK3β/β-Catenin Signaling Pathway

Figure 2

CWP can inhibit the invasion and migration of SGC-7901 cells. (a) Transwell experiments were performed on SGC-7901 cells for 24 h with different concentrations of CWP. The cells were inserted into the lower chamber through the basement membrane, and the basement membrane was stained and observed under a microscope. (b) SGC-7901 cells seeded on six-well plates were divided into four groups. After administration for 24 hours, the cells migration was recorded. (c) The histogram shows the number of SGC-7901 cells passing through the 8 μm pore size into the lower chamber. (d) The histogram shows the percentage of wound healing in SGC-7901 cells after 24 h. (e) SGC-7901 cells were treated with different dosages of CWP for 24 h on the condition of wound-healing assay. The inhibition of each group was detected with MTT assay. Data are expressed as the mean ± SD of three experiments ( < 0.05 compared with control group; < 0.01 compared with control group).

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