The Hypocholesterolemic Effects of Eryngium carlinae F. Delaroche Are Mediated by the Involvement of the Intestinal Transporters ABCG5 and ABCG8

Table 1

Experimental groups.

Number	Experimental group	Treatment
(1)	Control	Standard diet (Laboratory Rodent Diet 5001) ad libitum
(2)	Hypercholesterolemia	Hypercholesterolemic diet (1% cholesterol, 0.5% cholic acid) ad libitum
(3)	Ezetimibe	Ezetimibe 10 mg/kg and hypercholesterolemic diet ad libitum (Merck/Schering-Plough Pharmaceuticals, USA)
(4)	Hydroalcoholic extract	Extract of Eryngium carlinae at a dose of 100 mg/kg and hypercholesterolemic diet and water ad libitum
(5)	Hydroalcoholic extract	Extract of Eryngium carlinae at a dose of 500 mg/kg and hypercholesterolemic diet ad libitum
(6)	Hexa-O-acetyl-D-mannitol	Mannitol hexaacetate at a dose of 10 mg/kg and hypercholesterolemic diet ad libitum
(7)	D-Mannitol	D-Mannitol at a dose of 10 mg/kg and hypercholesterolemic diet ad libitum

Different treatments during the evaluation of Eryngium carlinae. All treatments were administered every day at 15:00 h for four weeks.