iTRAQ-Based Quantitative Proteomics Analysis of the Protective Effect of Yinchenwuling Powder on Hyperlipidemic Rats

Table 4

Significant differential expressions of proteins in YCL-treated rats and the model rats.

Accession	Sequence coverage (%)	Peptides (95%)	Gene name	Protein name	115 : 113	119 : 113	115 : 116	119 : 116
Immune
M0RBF1	71.26	126	C3	Complement C3	0.488	0.296	0.597	0.363
P08649	38.51	46	C4	Complement C4	0.421	0.360	0.560	0.483
G3V9R2	52.15	56	Cfh	Protein Cfh	0.575	0.402	0.766	0.535
P55314	39.73	16	C8b	Complement component C8 beta chain	0.497	0.334	0.718	0.479
B0BNN4	33.12	8	Cfp	Complement factor properdin	0.692	0.511	0.832	0.619
Q811M5	22.81	8	C6	Complement component C6	0.550	0.466	0.895	0.766
D3ZPI8	61.59	7	C8g	Complement component 8, gamma polypeptide (predicted), isoform CRA_a	0.685	0.698	0.637	0.655
Lipid metabolism and transport
Q5I0M1	65.22	17	ApoH	Apolipoprotein H	0.520	0.445	0.530	0.461
Inflammation
P11762	93.33	48	Lgals1	Galectin-1	0.525	0.711	0.417	0.565
Q8K3R4	48.36	12	Adipoq	30 kDa adipocyte complement-related protein	2.168	1.854	1.786	2.089
A0A0G2K4G5	21.41	12	Fndc1	Fibronectin type III domain-containing protein 1	0.425	0.525	0.780	0.946
Coagulation and hemostatic processes
P14480	73.28	26	Fgb	Fibrinogen beta chain	0.555	0.433	0.832	0.649
P02680	54.83	20	Fgg	Fibrinogen gamma chain	0.457	0.328	0.711	0.511
P08934	30.99	10	Kng1	Kininogen-1	0.655	0.625	0.667	0.631
Oxidation and antioxidation
B6DYP8	72.40	20	Gsta1	Glutathione S-transferase	2.270	1.247	2.249	1.236

Database accession numbers; percent sequence coverage of significantly differentially expressed proteins; name and categories of the proteins identified; ratios of treatments/models.