Research Article

Effect of Keishibukuryogan, a Japanese Traditional Kampo Prescription, on Improvement of Microcirculation and Oketsu and Induction of Endothelial Nitric Oxide: A Live Imaging Study

Figure 1

Live imaging of murine subcutaneous vessels before and after the administration of Keishibukuryogan. Representative images are shown. (a) shows the image before Keishibukuryogan administration, while (b)–(e) show images of the same site at 30, 60, 90, and 120 min after administration. (f) shows the change in vascular diameter at sites D1–D3 shown in (a)–(e). Maximum vasodilation from 60 to 90 min after Keishibukuryogan administration was confirmed. The vascular diameter was restored to preadministration levels at approx. 180 min.
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