Screening of Natural Bioactive Metabolites and Investigation of Antioxidant, Antimicrobial, Antihyperglycemic, Neuropharmacological, and Cytotoxicity Potentials of Litsea polyantha Juss. Ethanolic Root Extract
Table 3
Neuropharmacological effect of ethanolic extract of Litsea polyantha on hole cross test.
Treatment (oral) group
Number of holes crossed by the mice
0 min
30 min
60 min
90 min
120 min
180 min
Negative control
10.2 ± 0.80
8.6 ± 0.51
8.2 ± 0.58
7.6 ± 0.51
6.6 ± 0.5
8.6 ± 0.92
Positive control (diazepam)
9.4 ± 0.51
2.4 ± 0.4
1.8 ± 0.37
1.4 ± 0.51
2.0 ± 0.70
2.2 ± 0.37
Root 250 mg/kg
10.8 ± 0.37
8.0 ± 0.55
7.8 ± 0.37
7.0 ± 0.32
6.0 ± 0.32
7.8 ± 0.37
Root 500 mg/kg
10.2 ± 0.37
7.6 ± 0.51
6.4 ± 0.51
5.2 ± 0.37
5.0 ± 0.32
6.4 ± 0.24
,, and when compared with negative control. The significance level for individual experiment period has been shown in Supplementary Table .
