Screening of Natural Bioactive Metabolites and Investigation of Antioxidant, Antimicrobial, Antihyperglycemic, Neuropharmacological, and Cytotoxicity Potentials of Litsea polyantha Juss. Ethanolic Root Extract
Table 4
Neuropharmacological effect of ethanolic extract of Litsea polyantha on hole board test.
Treatment (oral) group
Amount of head dipping by the mice
0 min
30 min
60 min
90 min
120 min
180 min
Negative control
17 ± 0.71
22 ± 1.14
18 ± 0.71
21.4 ± 0.75
25 ± 0.71
29.2 ± 0.66
Positive control (diazepam)
19 ± 0.71
11.6 ± 0.51
8.4 ± 0.51
6 ± 0.45
3.2 ± 0.37
7 ± 0.45
Root 250 mg/kg
19.8 ± 0.86
18.4 ± 0.51
15.4 ± 0.51
14.2 ± 0.37
19 ± 0.71
20.6 ± 0.57
Root 500 mg/kg
19.2 ± 0.37
17.4 ± 0.51
15 ± 0.71
14.8 ± 0.58
18 ± 0.71
20.4 ± 0.93
,, and when compared with negative control. The significance level for individual experiment period has been shown in Supplementary Table .
