Electroacupuncture at ST36 Protects ICC Networks via mSCF/Kit-ETV1 Signaling in the Stomach of Diabetic Mice

Figure 1

Immunofluorescence of the ICC-MY (a)–(e) and ICC-IM (f)–(j) in the antrum labelled with Ano1 (green) and c-Kit (red). In the control group, the ICC networks of Ano1 and c-Kit were nearly completely overlapping, and both of the labels showed dense and intact ICC networks. The networks of the ICC in the MY and IM were incomplete, with destroyed processes in the DM and SEA groups. However, in the LEA and HEA groups, the ICC networks had nearly recovered to the normal level, and the two markers of the ICC indicated that there were long and abundant branches. The white arrowheads showed Ano1 positive c-Kit dim or negative cells. Scale bars = 100 μm and refer to all panels.