Electroacupuncture at ST36 Protects ICC Networks via mSCF/Kit-ETV1 Signaling in the Stomach of Diabetic Mice

Figure 2

Immunofluorescence of the ICC-MY (a)–(e) and ICC-IM (f)–(j) in the corpus labelled with Ano1 (green) and c-Kit (red). In the control group, the ICC networks indicated by Ano1 and c-Kit were all bright, and the integrity was maintained in both MY and IM. The two markers for the ICC networks were very dim, and the networks were severely disrupted in the DM group. Similar changes in the ICC networks were also observed in the SEA group. However, in the LEA and HEA groups, ICC-MY and ICC-IM still remained relatively intact, and the brightness of the two markers was almost normal. The white arrowheads show the Ano1 positive c-Kit dim or negative cells. Scale bars = 100 μm and refer to all panels.