¹H NMR-Based Metabonomic Study of Functional Dyspepsia in Stressed Rats Treated with Chinese Medicine Weikangning

Figure 4

(a) OPLS-DA score plot of model group (MS) and normal control group (NS) on predose day 4, displaying the degree of separation of the model between the MS (black squares) and NS group (red dots) ( = 24.2%, = 83.0%, and = 38.9%); (b) OPLS-DA corresponding color-coded correlation coefficient loading plot of key metabolites based on the metabolic information from MS and NS on predose day 4, demonstrating discrimination of key metabolite levels between the two groups; (c) OPLS-DA score plot of MS and Weikangning-treated group (WKN) on postdose day 11, showing the degree of separation between the MS (black squares) and WKN groups (blue diamonds) ( = 32.6%, = 94.2%, and = 71.1%); (d) OPLS-DA corresponding color-coded correlation coefficient loading plot of key metabolites based on the metabolic information from MS and WKN groups on postdose day 11, showing differences in levels of key metabolites between the two groups.

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