Evidence-Based Complementary and Alternative Medicine / 2017 / Article / Tab 3

Research Article

1H NMR-Based Metabonomic Study of Functional Dyspepsia in Stressed Rats Treated with Chinese Medicine Weikangning

Table 3

Quantitative comparison of metabolites identified in serum of model group (MS) and normal control group (NS).

MetabolitesChemical shiftIntegral in MS group (mean ± S.D.) × 10−2Integral in NS group (mean ± S.D.) × 10−2
( > 0.632)
(P < 0.05)

Isoleucine0.94 (t)0.146 ± 0.0370.116 ± 0.0200.702 (↑)2.3500.035
Leucine0.96 (dd)0.220 ± 0.0430.193 ± 0.0190.693 (↑)2.3680.010
Proline2.07 (m)0.085 ± 0.0140.067 ± 0.0060.661 (↑)2.2270.002
Methanol3.36 (s)0.385 ± 0.1650.195 ± 0.0320.769 (↑)2.6740.005
Glucose3.705 (t)0.314 ± 0.1140.425 ± 0.090−0.642 (↓)2.2370.026

The relative integrals of metabolites were determined by 1D 1H NMR analysis of urine. The values of the correlation number extracted from the correlation plots of OPLS-DA models of MS versus NS groups. The P values were obtained from Independent-Samples t-test or -test (shown with ). The P values were calculated by Mann–Whitney U test of nonparametric tests and the related integrals were presented in median ± IQR. The arrows (↑/↓) denote higher/lower amounts relative to NS group.

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