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Evidence-Based Complementary and Alternative Medicine
Volume 2017 (2017), Article ID 4109828, 6 pages
https://doi.org/10.1155/2017/4109828
Research Article

Reduced MLH3 Expression in the Syndrome of Gan-Shen Yin Deficiency in Patients with Different Diseases

1Department of Chinese Medicine, Changhai Hospital, Second Military Medical University, Shanghai 200433, China
2Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
3E-Institute of TCM Internal Medicine, Shanghai Municipal Education Commission, Shanghai 201203, China

Correspondence should be addressed to Changquan Ling

Received 7 January 2017; Revised 27 March 2017; Accepted 3 April 2017; Published 26 September 2017

Academic Editor: I-Min Liu

Copyright © 2017 Juan Du et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. K. Diaoyuan and S. Yongxia, “A brief history of human constitutionology,” Journal of Traditional Chinese Medicine, vol. 26, no. 3, pp. 230–238, 2006. View at Google Scholar · View at Scopus
  2. L. Weng, J. Du, W.-T. He, and C.-Q. Ling, “Characteristic genomics of peripheral blood mononuclear cells of hepatocellular carcinoma patients with liver-kidney yin deficiency syndrome,” Journal of Chinese Integrative Medicine, vol. 10, no. 4, pp. 406–415, 2012. View at Publisher · View at Google Scholar · View at Scopus
  3. C. S. o. L. Cancer, “The standard of clinical diagnosis and staging of primary liver cancer,” Chinese Journal of Hepatology, vol. 9, 2001. View at Google Scholar
  4. J. D. Lin, J. S. Lin, L. L. Chen, C. H. Chang, Y. C. Huang, and Y. C. Su, “BCQs: a body constitution questionnaire to assess stasis in traditional Chinese medicine,” European Journal of Integrative Medicine, vol. 4, no. 4, pp. e379–e391, 2012. View at Publisher · View at Google Scholar · View at Scopus
  5. J. S. Lin, L. L. Chen, J. D. Lin et al., “BCQ-: a body constitution questionnaire to assess Yin-Xu. Part II: evaluation of reliability and validity,” Forschende Komplementarmedizin, vol. 19, no. 6, pp. 285–292, 2012. View at Publisher · View at Google Scholar · View at Scopus
  6. J. Li, J. Du, D. Liu et al., “Ginsenoside Rh1 potentiates dexamethasone's anti-inflammatory effects for chronic inflammatory disease by reversing dexamethasone-induced resistance,” Arthritis Research and Therapy, vol. 16, no. 3, article R106, 2014. View at Publisher · View at Google Scholar · View at Scopus
  7. W. Zhang, J. Li, S. Qiu, J. Chen, and Y. Zheng, “Effects of the exopolysaccharide fraction (EPSF) from a cultivated Cordyceps sinensis on immunocytes of H22 tumor bearing mice,” Fitoterapia, vol. 79, no. 3, pp. 168–173, 2008. View at Publisher · View at Google Scholar · View at Scopus
  8. I. Brochu, M. Houde, L. Desbiens et al., “High salt-induced hypertension in B2 knockout mice is corrected by the ETA antagonist, A127722,” British Journal of Pharmacology, vol. 170, no. 2, pp. 266–277, 2013. View at Publisher · View at Google Scholar · View at Scopus
  9. B. Soria, E. Roche, G. Berna, T. Leon-Quinto, J. A. Reig, and F. Martin, “Insulin-secreting cells derived from embryonic stem cells normalize glycemia in streptozotocin-induced diabetic mice,” Diabetes, vol. 49, no. 2, pp. 157–162, 2000. View at Publisher · View at Google Scholar · View at Scopus
  10. C. Hoffmann, A. Rosenberger, W. Troeger, R. Stange, and M. Buehring, “Validation of questionnaires from several medical fields regarding the constitution of patients,” Forschende Komplementärmedizin und Klassische Naturheilkunde, vol. 9, no. 1, pp. 37–44, 2002. View at Publisher · View at Google Scholar
  11. E. Cannavo, G. Marra, J. Sabates-Bellver et al., “Expression of the MutL homologue hMLH3 in human cells and its role in DNA mismatch repair,” Cancer Research, vol. 65, no. 23, pp. 10759–10766, 2005. View at Publisher · View at Google Scholar · View at Scopus
  12. S. Santucci-Darmanin, S. Neyton, F. Lespinasse, A. Saunières, P. Gaudray, and V. Paquis-Flucklinger, “The DNA mismatch-repair MLH3 protein interacts with MSH4 in meiotic cells, supporting a role for this MutL homolog in mammalian meiotic recombination,” Human Molecular Genetics, vol. 11, no. 15, pp. 1697–1706, 2002. View at Publisher · View at Google Scholar · View at Scopus
  13. S. M. Lipkin, V. Wang, R. Jacoby et al., “MLH3: a DNA mismatch repair gene associated with mammalian microsatellite instability,” Nature Genetics, vol. 24, no. 1, pp. 27–35, 2000. View at Publisher · View at Google Scholar · View at Scopus
  14. W. Fan, G.Y., S. Li et al., “Development of the model of Long-term anger induced gen-shen Yin deficiency syndrome rats,” Chinese J Basic Med TCM, vol. 7, pp. 67–69, 2001. View at Google Scholar
  15. Z. Wu, H. Y. Yu, X. Ji, and B. Ouyang, “Evaluation of the characteristics of liver-kidney yin deficiency syndrome in late stage of spontaneously hypertension rats,” Chinese Journal of Information on TCM, vol. 23, pp. 58–61, 2016. View at Google Scholar