Evidence-Based Complementary and Alternative Medicine

Research Article

Systems Pharmacological Approach of Pulsatillae Radix on Treating Crohn’s Disease

Table 3

Highly expressed targets in Crohn’s disease.
UniProt IDTargetGene name
Q92887Canalicular multispecific organic anion transporter 1ABCC2
O60218Aldo-keto reductase family 1 member B10AKR1B10
P09917Arachidonate 5-lipoxygenaseALOX5
P62158CalmodulinCALM1
Q00534Cell division protein kinase 6CDK6
P10145Interleukin-8CXCL8
Q99814Endothelial PAS domain-containing protein 1EPAS1
P01100Proto-oncogene c-FosFOS
P47869Gamma-aminobutyric-acid receptor alpha-2 subunitGABRA2
P49841Glycogen synthase kinase-3 betaGSK3B
P09601Heme oxygenase 1HMOX1
P05362Intercellular adhesion molecule 1ICAM1
P01584Interleukin-1 betaIL1B
P05231Interleukin-6IL6
P03956Interstitial collagenaseMMP1
Q15788Nuclear receptor coactivator 1NCOA1
P35228Nitric oxide synthase, inducibleNOS2
P01111GTPase NRasNRAS
P11309Proto-oncogene serine/threonine-protein kinase Pim-1PIM1
P61925cAMP-dependent protein kinase inhibitor alphaPKIA
P00749Urokinase-type plasminogen activatorPLAU
P35354Prostaglandin G/H synthase 2PTGS2
P40763Signal transducer and activator of transcription 3STAT3
P17752Tryptophan 5-hydroxylase 1TPH1