Research Article
Efficacy and Safety of an Herbal Therapy in Patients with Amnestic Mild Cognitive Impairment: A 24-Week Randomized Phase III Trial
Table 4
Adverse events in the safety population.
| | Adverse | Herbal therapy | Donepezil | | () | () |
| | Any adverse events | 39 | 18.0% | 62 | 57.4% | | Abnormal alanine aminotransferase (ALT) | 1 | 0.5% | 1 | 0.9% | | Insomnia or abnormal dreams | | | 18 | 16.7% | | Skin rash | 0 | 0% | 1 | 0.9% | | Nausea | | | 18 | 16.7% | | Vomit | 0 | 0% | 5 | 4.2% | | Diarrhea | | | 14 | 12.5% | | Thirsty | 14 | 6.5% | 5 | 4.2% | | Sore throat | 9 | 4.2% | 0 | 0% | | Upper respiratory tract infection | 5 | 2.3% | 0 | 0% |
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Value are (%) of subjects. drug relationships considered probably and possibly drug related. indicates for the comparison with donepezil group.
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