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Evidence-Based Complementary and Alternative Medicine
Volume 2017 (2017), Article ID 4269868, 12 pages
https://doi.org/10.1155/2017/4269868
Review Article

Fraxinus: A Plant with Versatile Pharmacological and Biological Activities

1Department of Zoology, Faculty of Life Sciences, Government College University Faisalabad, Punjab 38000, Pakistan
2Department of Zoology, Faculty of Life Sciences, University of Sargodha, Punjab 40100, Pakistan

Correspondence should be addressed to Azhar Rasul; moc.liamg@lusarrahzard

Received 31 August 2017; Revised 24 October 2017; Accepted 7 November 2017; Published 27 November 2017

Academic Editor: Rainer W. Bussmann

Copyright © 2017 Iqra Sarfraz et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Fraxinus, a member of the Oleaceae family, commonly known as ash tree is found in northeast Asia, north America, east and western France, China, northern areas of Pakistan, India, and Afghanistan. Chemical constituents of Fraxinus plant include various secoiridoids, phenylethanoids, flavonoids, coumarins, and lignans; therefore, it is considered as a plant with versatile biological and pharmacological activities. Its tremendous range of pharmacotherapeutic properties has been well documented including anticancer, anti-inflammatory, antioxidant, antimicrobial, and neuroprotective. In addition, its bioactive phytochemicals and secondary metabolites can be effectively used in cosmetic industry and as a competent antiaging agent. Fraxinus presents pharmacological effectiveness by targeting the novel targets in several pathological conditions, which provide a spacious therapeutic time window. Our aim is to update the scientific research community with recent endeavors with specifically highlighting the mechanism of action in different diseases. This potentially efficacious pharmacological drug candidate should be used for new drug discovery in future. This review suggests that this plant has extremely important medicinal utilization but further supporting studies and scientific experimentations are mandatory to determine its specific intracellular targets and site of action to completely figure out its pharmacological applications.