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Evidence-Based Complementary and Alternative Medicine
Volume 2017, Article ID 4505194, 10 pages
https://doi.org/10.1155/2017/4505194
Review Article

Review on Research about Traditional Chinese Medicine in Cancer Stem Cell

1Department of Oncology, Guang’anmen Hospital, China Academy of Chinese Medicine Sciences, No. 5 Beixiange, Xicheng District, Beijing 100053, China
2Traditional Chinese Medicine Department, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100021, China

Correspondence should be addressed to Li Feng; moc.621@366ilgnef, Bingkui Piao; moc.361@321iukgniboaip, and Peitong Zhang; moc.liamtoh@gnotiepgnahzrd

Received 5 February 2017; Revised 23 May 2017; Accepted 15 June 2017; Published 4 October 2017

Academic Editor: Shuang-En Chuang

Copyright © 2017 Yaohan Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Cancer stem cells (CSCs) are small subpopulations of neoplastic cells within a tumor, which have self-renewal and differentiation abilities and could generate new tumors with few cells. Researches have showed that CSCs are considered the most likely reason for cancer recurrence and metastasis. Accumulating evidences have showed that traditional Chinese medicine (TCM) has significant effect on CSCs. It could inhibit the proliferation, self-renew, and multidifferentiation of CSCs. We aimed to summarize the theories of CSCs in TCM, the inhibitory effect, and the pathway on CSCs of TCM. This review will provide potential new strategies and alternative perspectives for CSCs treatments and basic research into complementary and alternative medicine.