Evidence-Based Complementary and Alternative Medicine / 2017 / Article / Tab 6

Review Article

Commercial Essential Oils as Potential Antimicrobials to Treat Skin Diseases

Table 6

Essential oil studies showing efficacy against other bacterial skin pathogens.

Essential Species Main Reference

Achillea millefolium (yarrow)MICC. perfringens KUKENS-TurkeyTween 804.50 mg/mLEucalyptol (24.60%), camphor (16.70%), α-terpineol (10.20%)[112]
Achillea setacea (bristly yarrow)0.56 mg/mLSabinene (10.80%), eucalyptol (18.50%) [113]
Achillea teretifolia (yarrow)0.28 mg/mLEucalyptol (19.90%), camphor (11.10%), borneol (11.90%)

Eucalyptus globulus (eucalyptus)MICS. pyogenes (ATCC 12344)Tween 8010.00 mg/mL1,8-Cineol (81.93%) [128]
S. pyogenes (NHLS 8668)0.50 mg/mL

Eucalyptus radiata (eucalyptus)MICS. pyogenes (NHLS 8668)Acetone0.50–1.00 mg/mL1,8-Cineole , -terpineol [130]
Eucalyptus camaldulensis (eucalyptus)Acetone0.50 mg/mL
Eucalyptus citriodora (eucalyptus)Acetone1.00 mg/mL
Eucalyptus smithii (eucalyptus)Acetone0.50 mg/mL
Eucalyptus dives (eucalyptus)Acetone

Juniperus excelsa (juniper), berries, DojranADMS. pyogenes (clinical isolate)50% DSMO>50.00%-Pinene (70.81%) [87]
H. influenzae (clinical isolate)31.00 μL/mL
Juniperus excelsa (juniper), berries, OhridS. pyogenes (clinical isolate)>50.00%Sabinene (58.85%)
H. influenzae (clinical isolate)
Juniperus excelsa (juniper), leaves, DojranH. influenzae (clinical isolate)>50.00%-Pinene (33.83%), cedrol (24.44%)
Juniperus excelsa (juniper), leaves, OhridS. pyogenes (clinical isolate)125.00 μL/mLSabinene (29.49%), cis-thujone (26.20%), menth-2-en-1-ol (12.86%)
H. influenzae (clinical isolate)

Juniperus officinalis (juniper berry)MICS. pyogenes (ATCC 12344)Tween 8020.00 mg/mL-Pinene (39.76%)[128]

Kunzea ericoides (Kānuka)MACC. diphtheriae (clinical isolate)Tween 800.25% v/v-Pinene (61.60%) [137]
C. minutissimus (clinical isolate)0.30% v/v
MICS. pyogenes (ATCC 8668)Acetone2.00 mg/mL-Pinene (26.2–46.7%), p-cymene (5.8–19.1%) [138]
B. brevis (ATCC 8246)1.00 mg/mL
B. agri (ATCC 51663)
B. laterosporus (ATCC 64)

Leptospermum scoparium (manuka)MACC. diphtheriae (clinical isolate)Tween 800.05% v/v(−)-()-Calamenene (14.50%), leptospermone (17.60%) [137]
C. minutissimus (clinical isolate)
MICS. pyogenes (ATCC 8668)Acetone1.00 mg/mLEudesma-4(14),11-diene (6.2–14.5%), -selinene (5.90–13.5%), ()-methyl cinnamate (9.2–19.5%) [138]
B. brevis (ATCC 8246)
B. agri (ATCC 51663)0.06 mg/mL
B. laterosporus (ATCC 64)0.25 mg/mL

Melaleuca alternifolia (tea tree)MICCorynebacterium spp. (10 clinical isolates)Tween 800.06–2% v/vTerpinen-4-ol (35.70%)[152]
MIC90S. pyogenes (15 clinical isolates)0.12%[235]
MICC. diphtheriae (clinical isolate)Tween 800.20% v/v-Terpinene (11.40%), -terpinene (22.50%), terpinen-4-ol (35.20%) [137]
C. minutissimus (clinical isolate)

Melaleuca cajuputi (cajuput)MICS. pyogenes (ATCC 12344)Tween 805.00 mg/mL1,8-Cineol (67.60%)[128]
MACC. diphtheriae (clinical isolate)0.30% v/v1,8-Cineole (55.50%) [137]
C. minutissimus (clinical isolate)

Melaleuca quinquenervia (niaouli)MACC. diphtheriae (clinical isolate)Tween 800.25% v/v1,8-Cineole (61.20%) [137]
C. minutissimus (clinical isolate)

Mentha piperita (peppermint)MICS. pyogenes (ATCC 12344)Tween 805.00 mg/mL1,8-Cineol (12.06%), menthone (22.24%), menthol (47.29%)[128]

name (common name), part of plant (if applicable).
: microdilution method; MAC: macrodilution method; ADM: agar dilution method; CTA: contact time assay.
Type Culture Collection, Rockville, USA (ATCC).
concentration was not included; n.m.: not mentioned.
: no inhibition.
: no composition results reported.