Huang Gan Formula Eliminates the Oxidative Stress Effects of Advanced Oxidation Protein Products on the Divergent Regulation of the Expression of AGEs Receptors via the JAK2/STAT3 Pathway

Figure 4

HGF reversed AOPP-induced ROS and NO production in a concentration-dependent fashion. ROS production is shown in (a) and (c) following 24 h of serum starvation. HMCs were pretreated with AOPP for 1.5 h ± HGF of the indicated concentrations for another 2 h; NO production is shown in (b). HMCs were pretreated with AOPP for 24 h ± HGF of the suggested concentrations for another 24 h. Data represent means ± SD; versus AOPPs; versus control; versus AOPPs; .

(a)

(b)

(c)