Antimicrobial Activities and Time-Kill Kinetics of Extracts of Selected Ghanaian Mushrooms

Table 4

MIC and MBC/MFC of crude methanol extracts of T. gibbosa, T. elegans, and reference drugs against test organisms.

Test organisms	T. gibbosa		T. elegans		Cipro	Keto
	MIC (mg/mL)	MBC (mg/mL)	MIC (mg/mL)	MBC (mg/mL)	MIC (µg/mL)	MIC (µg/mL)
E. coli	6	30	8	50	≤0.16	nd
P. aeruginosa	6	50	8	50	≤0.31	nd
S. pyogenes	6	30	8	50	≤0.31	nd
S. typhi	8	50	20	—	2	nd
S. aureus	6	30	6	30	≤0.31	nd
K. pneumonia	6	30	6	50	0.63	nd
B. subtilis	4	20	6	30	0.16	nd
E. faecalis	8	50	30	—	3.5	nd
C. albicans	20	—	6	30	nd	≤0.31
A. niger	—	—	—	—	nd	0.35
A. flavus	—	—	—	—	nd	0.50
A. tamarii	—	—	—	—	nd	2.00

MIC: minimum inhibitory concentration; MBC: minimum bactericidal concentration; nd = not determined; — = MIC/MBC not present / > highest test concentration (50 mg/mL); Cipro = ciprofloxacin; Keto = ketoconazole.