Antimicrobial Activities and Time-Kill Kinetics of Extracts of Selected Ghanaian Mushrooms

Table 5

MIC and MBC/MFC of crude methanol extracts of V. volvacea, S. commune, and reference drugs (ciprofloxacin and ketoconazole) against test organisms.

Test organisms	V. volvacea		S. commune		Cipro	Keto
	MIC (mg/mL)	MBC (mg/mL)	MIC (mg/mL)	MBC (mg/mL)	MIC (µg/mL)	MIC (µg/mL)
P. aeruginosa	10	50	8	50	≤0.31	nd
S. pyogenes	8	50	8	50	≤0.31	nd
S. typhi	—	—	—	—	2.00	nd
S. aureus	8	50	6	30	≤0.31	nd
K. pneumonia	6	30	6	30	0.63	nd
B. subtilis	—	—	—	—	nd	nd
E. faecalis	—	—	—	—	3.50	nd
C. albicans	20	—	10	50	0.16	≤0.31
A. niger	—	—	—	—	nd	0.35
A. flavus	—	—	—	—	nd	0.50
A. tamarii	—	—	—	—	nd	2.00

MIC: minimum inhibitory concentration; MBC: minimum bactericidal concentration; nd = not determined; — = MIC/MBC not present / > highest test concentration (50 mg/mL); Cipro = ciprofloxacin; Keto = ketoconazole.