Research Article

The Effect of Chunghyul-Dan on Hyperventilation-Induced Carbon Dioxide Reactivity of the Middle Cerebral Artery in Normal Subjects: A Dose-Dependent Study

Table 3

Changes in corrected blood flow velocity at = 40 mmHg (CV40, cm/sec) before and after CHD administration.

()(T0) Before administrationAfter administration
T1 (1 hr)T2 (2 hr)T3 (3 hr)

Control0.0020.071
CHD300 mg0.061
CHD600 mg0.024
CHD1200 mg0.255

Mean ± SD values are shown. CHD, chunghyul-dan; hr, hour.
: time × treatment interaction by two-way repeated measures analysis of variation (RM ANOVA).
No significant difference between each group (Bonferroni multiple comparisons).
: time effect of individual treatment by one-way RM ANOVA.
No significant difference between individual time points (Bonferroni multiple comparisons).