The Effect of Chunghyul-Dan on Hyperventilation-Induced Carbon Dioxide Reactivity of the Middle Cerebral Artery in Normal Subjects: A Dose-Dependent Study

Table 4

Changes in mean blood pressure and heart rate before and after CHD administration.

		(T0) Before administration	After administration
			T1 (1 hr)	T2 (2 hr)	T3 (3 hr)
Mean blood pressure (mmHg)
Control						0.742	0.736
CHD	300 mg						0.695
CHD	600 mg						0.611
CHD	1200 mg						0.518
Heart rate (beats per minute)
Control						0.791	0.154
CHD	300 mg						0.085
CHD	600 mg						0.374
CHD	1200 mg						0.356

All data are means ± SD. CHD, chunghyul-dan; hr, hour.
: time × treatment interaction by two- way repeated measures analysis of variation (RM ANOVA).
: time effect of individual groups by one-way RM ANOVA.