Linarin Enriched Extract Attenuates Liver Injury and Inflammation Induced by High-Fat High-Cholesterol Diet in Rats

Figure 3

Lin-extract improved liver inflammation induced by HFHC diet. Lin-extract dose-dependently suppressed the expression of inflammation cytokines (a) TNF-α, (b) MCP-1, and (c) CXCL1. Values are expressed as the mean ± SEM (). (, control versus model; , model versus intervention group). Lin-extract improved inflammation infiltration. (d) HE staining in representative sections at 100x magnification. Green arrow points to inflammation foci. Cont, control; LIN-LD, low dose Lin-extract; LIN-MD, middle dose Lin-extract; LIN-HD, high dose Lin-extract; TNF-α, tumor necrosis factor-α; MCP-1, monocyte chemotactic protein-1; and CXCL1, chemokine (C-X-C motif) ligand 1. , control versus model.

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