Research Article

A 4-Week Repeated-Dose Oral Toxicity Study of Bojungikgi-Tang in Crl:CD Sprague Dawley Rats

Table 2

Mortality and clinical signs in rats treated with BJIGT for 4 weeks.

GroupDosing phase
Scratch wound,
1 day≤1 week≤2 weeks≤4 weeksFinal

Male
 0 mg/kg/day
 500 mg/kg/day
 1000 mg/kg/day
 2000 mg/kg/day
Female
 0 mg/kg/day
 500 mg/kg/day
 1000 mg/kg/day
 2000 mg/kg/day

Number of animals with dead animals/total animal number. of animals with sign animals/total animal number.