Research Article

A 4-Week Repeated-Dose Oral Toxicity Study of Bojungikgi-Tang in Crl:CD Sprague Dawley Rats

Table 4

Serum biochemical parameters of male rats treated with BJIGT for 4 weeks.

Dose (mg/kg/day)050010002000050010002000

MaleFemale
Glucose (mg/dL)
BUN (mg/dL)
Creatinine (mg/dL)
Creatine kinase (IU/L)
Total protein (g/dL)
Albumin (g/dL)
Albumin/globulin ratio
AST (IU/L)
ALT (IU/L)
GGT (IU/L)
Total bilirubin (mg/dL)
Total cholesterol (mg/dL)
Triglycerides (mg/dL)
Phospholipid (mg/dL)
ALP (IU/L)
Ca (mg/dL)
IP (mg/dL)
K (mmol/L)
Na (mmol/L)
Cl (mmol/L)

Results are presented as mean ± SD. indicates significance at the level. BUN, blood urea nitrogen; CK, creatine kinase; AG, albumin/globulin ratio; AST, aspartate aminotransferase; ALT, alanine aminotransferase; GGT, gamma glutamyl transpeptidase; TB, total bilirubin; TCHO, total cholesterol; TG, triglyceride; PL, phospholipid; ALP, alkaline phosphatase; IP, inorganic phosphorus.