Research Article

Extract of Fructus Cannabis Ameliorates Learning and Memory Impairment Induced by D-Galactose in an Aging Rats Model

Figure 9

Proposed mechanism of the effect of EFC on ameliorating cognitive impairment induced by D-gal. EFC could relieve age-related cognitive impairment by attenuating oxidative stress, improving immune function, and inhibiting the activation of astrocytes as well as attenuating tau phosphorylation and suppressing PS1 expression in the brain of D-gal treated rats.