Research Article

Acute and Subacute Oral Toxicity Evaluation of Eriobotrya japonica Leaf Triterpene Acids in ICR Mice

Table 1

Acute oral toxicity study of ELTA in ICR mice. All data are expressed as means ± SD ( in each group), for all ELTA treated groups compared with the control group. piloerection symptom was observed in 1/5 mice and disappeared within 48 h after drug administration. piloerection symptom was observed in 2/5 mice and disappeared within 48 h after drug administration.

SexELTA dose (g⋅kg−1 BW)Body weight (g)Dead/totalSymptoms
1st day14th day

Male0.300/5None
0.650/5None
1.390/5None
3.000/5Pilo

Female0.300/5None
0.650/5None
1.390/5None
3.000/5Pilo