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Evidence-Based Complementary and Alternative Medicine
Volume 2017, Article ID 4874865, 10 pages
https://doi.org/10.1155/2017/4874865
Research Article

Effects of Achyrocline satureioides Inflorescence Extracts against Pathogenic Intestinal Bacteria: Chemical Characterization, In Vitro Tests, and In Vivo Evaluation

1Departamento de Bioquímica, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil
2Faculdade de Ciências da Saúde, Centro Universitário Ritter dos Reis (UniRitter), Porto Alegre, RS, Brazil
3Instituto de Ciência e Tecnologia de Alimentos, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil
4Instituto de Tecnologia do Petróleo, Pontíficia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, RS, Brazil
5Instituto de Quimica, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil
6Faculdade de Farmácia, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil

Correspondence should be addressed to Karla Suzana Moresco; moc.liamg@ocseromalrak

Received 6 May 2017; Revised 23 June 2017; Accepted 17 July 2017; Published 7 September 2017

Academic Editor: Daniela Rigano

Copyright © 2017 Karla Suzana Moresco et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. Davies and D. Davies, “Origins and evolution of antibiotic resistance,” Microbiology and Molecular Biology Reviews, vol. 74, no. 3, pp. 417–433, 2010. View at Publisher · View at Google Scholar · View at Scopus
  2. C. Casero, A. Estévez-Braun, Á. G. Ravelo, M. Demo, S. Méndez-Álvarez, and F. MacHín, “Achyrofuran is an antibacterial agent capable of killing methicillin-resistant vancomycin-intermediate Staphylococcus aureus in the nanomolar range,” Phytomedicine, vol. 20, no. 2, pp. 133–138, 2013. View at Publisher · View at Google Scholar · View at Scopus
  3. I. Cho and M. J. Blaser, “The human microbiome: at the interface of health and disease,” Nature Reviews Genetics, vol. 13, no. 4, pp. 260–270, 2012. View at Publisher · View at Google Scholar · View at Scopus
  4. A. B. Shreiner, J. Y. Kao, and V. B. Young, “The gut microbiome in health and in disease,” Current Opinion in Gastroenterology, vol. 31, no. 1, pp. 69–75, 2015. View at Publisher · View at Google Scholar · View at Scopus
  5. N.-R. Shin, T. W. Whon, and J.-W. Bae, “Proteobacteria: microbial signature of dysbiosis in gut microbiota,” Trends in Biotechnology, vol. 33, no. 9, pp. 496–503, 2015. View at Publisher · View at Google Scholar · View at Scopus
  6. K. Forslund, F. Hildebrand, T. Nielsen et al., “Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota,” Nature, vol. 528, no. 7581, pp. 262–266, 2015. View at Publisher · View at Google Scholar · View at Scopus
  7. R. E. Ley, P. J. Turnbaugh, S. Klein, and J. I. Gordon, “Microbial ecology: human gut microbes associated with obesity,” Nature, vol. 444, no. 7122, pp. 1022-1023, 2006. View at Publisher · View at Google Scholar · View at Scopus
  8. Y. J. Kim, E.-H. Kim, and K. B. Hahm, “Oxidative stress in inflammation-based gastrointestinal tract diseases: challenges and opportunities,” Journal of Gastroenterology and Hepatology, vol. 27, no. 6, pp. 1004–1010, 2012. View at Publisher · View at Google Scholar · View at Scopus
  9. B. H. Havsteen, “The biochemistry and medical significance of the flavonoids,” Pharmacology and Therapeutics, vol. 96, no. 2-3, pp. 67–202, 2002. View at Publisher · View at Google Scholar · View at Scopus
  10. G. Di Carlo, N. Mascolo, A. A. Izzo, and F. Capasso, “Flavonoids: old and new aspects of a class of natural therapeutic drugs,” Life Sciences, vol. 65, no. 4, pp. 337–353, 1999. View at Publisher · View at Google Scholar · View at Scopus
  11. J. B. Harborne and C. A. Williams, “Advances in flavonoid research since 1992,” Phytochemistry, vol. 55, no. 6, pp. 481–504, 2000. View at Publisher · View at Google Scholar · View at Scopus
  12. F. Cardona, C. Andrés-Lacueva, S. Tulipani, F. J. Tinahones, and M. I. Queipo-Ortuño, “Benefits of polyphenols on gut microbiota and implications in human health,” Journal of Nutritional Biochemistry, vol. 24, no. 8, pp. 1415–1422, 2013. View at Publisher · View at Google Scholar · View at Scopus
  13. H. C. Lee, A. M. Jenner, C. S. Low, and Y. K. Lee, “Effect of tea phenolics and their aromatic fecal bacterial metabolites on intestinal microbiota,” Research in Microbiology, vol. 157, no. 9, pp. 876–884, 2006. View at Publisher · View at Google Scholar · View at Scopus
  14. D. Retta, E. Dellacassa, J. Villamil, S. A. Suárez, and A. L. Bandoni, “Marcela, a promising medicinal and aromatic plant from Latin America: a review,” Industrial Crops and Products, vol. 38, no. 1, pp. 27–38, 2012. View at Publisher · View at Google Scholar · View at Scopus
  15. M. Polydoro, K. C. B. De Souza, M. E. Andrades et al., “Antioxidant, a pro-oxidant and cytotoxic effects of Achyrocline satureioides extracts,” Life Sciences, vol. 74, no. 23, pp. 2815–2826, 2004. View at Publisher · View at Google Scholar · View at Scopus
  16. M. B. Joray, S. M. Palacios, and M. C. Carpinella, “Understanding the interactions between metabolites isolated from Achyrocline satureioides in relation to its antibacterial activity,” Phytomedicine, vol. 20, no. 3-4, pp. 258–261, 2013. View at Publisher · View at Google Scholar · View at Scopus
  17. C. Casero, F. Machín, S. Méndez-Álvarez et al., “Structure and antimicrobial activity of phloroglucinol derivatives from Achyrocline satureioides,” Journal of Natural Products, vol. 78, no. 1, pp. 93–102, 2015. View at Publisher · View at Google Scholar · View at Scopus
  18. J. Bidone, V. C. Bica, P. R. Petrovick et al., “Simultaneous quantification of flavonoids from Achyrocline satureioides by a polra-reversed phase LC method-application to skin permeation/retention studies,” Pharmazie, vol. 69, no. 1, pp. 5–9, 2014. View at Publisher · View at Google Scholar · View at Scopus
  19. K. C. B. De Souza, V. L. Bassani, and E. E. S. Schapoval, “LC determination of flavonoids: separation of quercetin, luteolin and 3-O-methylquercetin in Achyrocline satureioidespreparations,” Phytomedicine, vol. 14, no. 2-3, pp. 102–108, 2007. View at Google Scholar
  20. AOAC—Association of Official Agricultural Chemists, Official Methods of Analysis of the Association of Agricultural Chemists, A.O.A.C., Washington, DC, USA, 12th edition, 1992.
  21. A. T. Duarte, M. B. Dessuy, M. G. R. Vale, B. Welz, and J. B. De Andrade, “Sequential determination of Cd and Cr in biomass samples and their ashes using high-resolution continuum source graphite furnace atomic absorption spectrometry and direct solid sample analysis,” Talanta, vol. 115, pp. 55–60, 2013. View at Publisher · View at Google Scholar · View at Scopus
  22. A. R. Borges, L. L. François, B. Welz, E. Carasek, and M. G. R. Vale, “Determination of fluorine in plant materials via calcium mono-fluoride using high-resolution graphite furnace molecular absorption spectrometry with direct solid sample introduction,” Journal of Analytical Atomic Spectrometry, vol. 29, no. 9, pp. 1564–1569, 2014. View at Publisher · View at Google Scholar · View at Scopus
  23. M. T. K. Dresch, S. B. Rossato, V. D. Kappel et al., “Optimization and validation of an alternative method to evaluate total reactive antioxidant potential,” Analytical Biochemistry, vol. 385, no. 1, pp. 107–114, 2009. View at Publisher · View at Google Scholar · View at Scopus
  24. I. F. F. Benzie and J. J. Strain, “The ferric reducing ability of plasma (FRAP) as a measure of "antioxidant power": the FRAP assay,” Analytical Biochemistry, vol. 239, no. 1, pp. 70–76, 1996. View at Publisher · View at Google Scholar · View at Scopus
  25. F. Chen, Z. Jia, K. C. Rice, R. A. Reinhardt, K. W. Bayles, and D. Wang, “The development of dentotropic micelles with biodegradable tooth-binding moieties,” Pharmaceutical Research, vol. 30, no. 11, pp. 2808–2817, 2013. View at Publisher · View at Google Scholar · View at Scopus
  26. G. K. B. Lopes, H. M. Schulman, and M. Hermes-Lima, “Polyphenol tannic acid inhibits hydroxyl radical formation from Fenton reaction by complexing ferrous ions,” Biochimica et Biophysica Acta (BBA)—General Subjects, vol. 1472, no. 1-2, pp. 142–152, 1999. View at Publisher · View at Google Scholar · View at Scopus
  27. Z. Du and W. J. Bramlage, “Modified thiobarbituric acid for measuring lipid oxidation in sugar-rich plant tissue extracts,” Journal of Agricuhural and Food Chemistry, vol. 40, no. 9, pp. 1566–1570, 1992. View at Publisher · View at Google Scholar · View at Scopus
  28. S. T. Bates, D. Berg-Lyons, J. G. Caporaso, W. A. Walters, R. Knight, and N. Fierer, “Examining the global distribution of dominant archaeal populations in soil,” The ISME Journal, vol. 5, no. 5, pp. 908–917, 2011. View at Publisher · View at Google Scholar · View at Scopus
  29. R. Schmieder and R. Edwards, “Quality control and preprocessing of metagenomic datasets,” Bioinformatics, vol. 27, no. 6, pp. 863-864, 2011. View at Publisher · View at Google Scholar · View at Scopus
  30. R. C. Edgar, “UPARSE: highly accurate OTU sequences from microbial amplicon reads,” Nature Methods, vol. 10, no. 10, pp. 996–998, 2013. View at Publisher · View at Google Scholar · View at Scopus
  31. J. R. Cole, Q. Wang, J. A. Fish et al., “Ribosomal Database Project: data and tools for high throughput rRNA analysis,” Nucleic Acids Research, vol. 42, no. 1, pp. D633–D642, 2014. View at Publisher · View at Google Scholar · View at Scopus
  32. J. G. Caporaso, J. Kuczynski, J. Stombaugh et al., “QIIME allows analysis of high-throughput community sequencing data,” Nature Methods, vol. 7, no. 5, pp. 335-336, 2010. View at Publisher · View at Google Scholar · View at Scopus
  33. T. Z. DeSantis, P. Hugenholtz, N. Larsen et al., “Greengenes, a chimera-checked 16S rRNA gene database and workbench compatible with ARB,” Applied and Environmental Microbiology, vol. 72, no. 7, pp. 5069–5072, 2006. View at Publisher · View at Google Scholar · View at Scopus
  34. A. S. Motta and A. Brandelli, “Characterization of an antibacterial peptide produced by brevibacterium linens,” Journal of Applied Microbiology, vol. 92, no. 1, pp. 63–70, 2002. View at Publisher · View at Google Scholar · View at Scopus
  35. E. D. Brown and G. D. Wright, “Antibacterial drug discovery in the resistance era,” Nature, vol. 529, no. 7586, pp. 336–343, 2016. View at Publisher · View at Google Scholar · View at Scopus
  36. Infectious Diseases Society of America, Statement of the IDSA Concerning "Bioshield II: Responding to an Ever-Changing Threat", IDSA, Va, USA, 2017.
  37. A. Rojas, L. Hernandez, R. Pereda-Miranda, and R. Mata, “Screening for antimicrobial activity of crude drug extracts and pure natural products from Mexican medicinal plants,” Journal of Ethnopharmacology, vol. 35, no. 3, pp. 275–283, 1992. View at Publisher · View at Google Scholar · View at Scopus
  38. T. P. T. Cushnie and A. J. Lamb, “Antimicrobial activity of flavonoids,” International Journal of Antimicrobial Agents, vol. 26, pp. 343–356, 2005. View at Google Scholar
  39. L. E. Alcaráz, S. E. Blanco, O. N. Puig, F. Tomás, and F. H. Ferretti, “Antibacterial activity of flavonoids against methicillin-resistant Staphylococcus aureus strains,” Journal of Theoretical Biology, vol. 205, no. 2, pp. 231–240, 2000. View at Publisher · View at Google Scholar · View at Scopus
  40. A. Mori, C. Nishino, N. Enoki, and S. Tawata, “Antibacterial activity and mode of action of plant flavonoids against Proteus vulgaris and Staphylococcus,” Phytochemistry, vol. 26, no. 8, pp. 2231–2234, 1987. View at Publisher · View at Google Scholar · View at Scopus
  41. M. Sato, H. Tsuchiya, M. Akagiri, N. Takagi, and M. Iinuma, “Growth inhibition of oral bacteria related to denture stomatitis by anti-candidal chalcones,” Australian Dental Journal, vol. 42, no. 5, pp. 343–346, 1997. View at Publisher · View at Google Scholar · View at Scopus
  42. F. Zeidán-Chuliá, J. L. Rybarczyk-Filho, M. Gursoy et al., “Bioinformatical and in vitro approaches to essential oil-induced matrix metalloproteinase inhibition,” Pharmaceutical Biology, vol. 50, no. 6, pp. 675–686, 2012. View at Publisher · View at Google Scholar · View at Scopus
  43. F. Zeidán-Chuliá, B.-H. Neves de oliveira, M. Gursoy et al., “MMP-REDOX/NO interplay in periodontitis and its inhibition with Satureja hortensis L. essential oil,” Chemistry and Biodiversity, vol. 10, no. 4, pp. 507–523, 2013. View at Publisher · View at Google Scholar · View at Scopus
  44. F. Zeidán-Chuliá, M. Keskin, E. Könönen et al., “Antibacterial and antigelatinolytic effects of Satureja hortensis L. essential oil on epithelial cells exposed to Fusobacterium nucleatum,” Journal of Medicinal Food, vol. 18, no. 4, pp. 503–506, 2015. View at Publisher · View at Google Scholar · View at Scopus
  45. S. C. Bischoff, G. Barbara, W. Buurman et al., “Intestinal permeability—a new target for disease prevention and therapy,” BMC Gastroenterology, vol. 14, article 189, 2014. View at Publisher · View at Google Scholar
  46. S. C. Bischoff, “'Gut health': a new objective in medicine?” BMC Medicine, vol. 9, article 24, 2011. View at Publisher · View at Google Scholar · View at Scopus
  47. N. Takahashi and J. Washio, “Metabolomic effects of xylitol and fluoride on plaque biofilm in vivo,” Journal of Dental Research, vol. 90, no. 12, pp. 1463–1468, 2011. View at Publisher · View at Google Scholar · View at Scopus