Research Article

In Vivo and In Vitro Evaluation of Pharmacological Potentials of Secondary Bioactive Metabolites of Dalbergia candenatensis Leaves

Table 5

Effect of D. candenatensis on thiopental sodium induced sleeping time in mice (mean ± SEM, ).

TreatmentDose
(mg/kg)
Onset of sleep
(min)
Duration of sleep
(min)

Control (1% v/v Tween-80 water)10 ml/kg1.94 ± 0.161.60 ± 3.87
Diazepam3 mg/kg0.81 ± 0.06152.60 ± 4.40
Test I100 mg/kg1.75 ± 0.0690.40 ± 3.40
Test II250 mg/kg1.59 ± 0.12113.20 ± 3.17
Test III500 mg/kg1.30 ± 0.07140.60 ± 3.19

indicates when compared with control.