Research Article
In Vivo and In Vitro Evaluation of Pharmacological Potentials of Secondary Bioactive Metabolites of Dalbergia candenatensis Leaves
Table 5
Effect of
D. candenatensis on thiopental sodium induced sleeping time in mice (mean ± SEM,
).
| Treatment | Dose (mg/kg) | Onset of sleep (min) | Duration of sleep (min) |
| Control (1% v/v Tween-80 water) | 10 ml/kg | 1.94 ± 0.1 | 61.60 ± 3.87 | Diazepam | 3 mg/kg | 0.81 ± 0.06 | 152.60 ± 4.40 | Test I | 100 mg/kg | 1.75 ± 0.06 | 90.40 ± 3.40 | Test II | 250 mg/kg | 1.59 ± 0.12 | 113.20 ± 3.17 | Test III | 500 mg/kg | 1.30 ± 0.07 | 140.60 ± 3.19 |
|
|
indicates when compared with control.
|