Research Article
Antiamylase, Anticholinesterases, Antiglycation, and Glycation Reversing Potential of Bark and Leaf of Ceylon Cinnamon (Cinnamomum zeylanicum Blume) In Vitro
Table 4
Anticholinesterases activity.
| |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Data represented as mean ± SEM ( each). Mean IC50 values in the column superscripted by different letters are significantly different at . Statistical analysis was carried out separately for acetylcholine esterase and butyrylcholine esterase inhibitory assays. IC50 galantamine, acetylcholine esterase inhibitory activity: 2.52 ± 0.17 µg/mL; IC50 galantamine, butyrylcholine esterase inhibitory activity: 74.80 ± 3.53 µg/mL. Ethanol bark, DCM : M bark, ethanol leaf, and DCM : M leaf = 0.97, 0.97, 0.94, and 0.98, respectively, for butyrylcholine esterase inhibitory activity. Ethanol bark, DCM : M bark, ethanol leaf, and DCM : M leaf = 0.92, 0.94, 0.95, and 0.99, respectively, for acetylcholine esterase inhibitory activity. DCM : M: dichloromethane : methanol. |