Effect of Mahuang Gancao Ganjiang Decoction on Fusion and Fission of Mitochondria and Apoptosis of Lymphocytes in Mice under Cold Stress

Figure 2

The ATP content and mitochondrial membrane potential of lymphocytes. (a) Cold stress caused the decrease of ATP content in lymphocytes. The ATP content of lymphocytes recovered after the mice treated by MGGD. versus control group; versus cold stress group. (b) Mitochondrial membrane potential of lymphocytes was measured by flow cytometry. The values mentioned in the lower right corner of each flow cytometric dot-plot indicate how much membrane potential decreased. Representative dot-plots of three independent experiments are shown. Compared with the mice kept under normal temperature, the mice suffering from cold stress had low mitochondrial membrane potential in lymphocytes. MGGD can make the mitochondrial membrane potential of lymphocytes recover to a certain extent.

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