Research Article

Astragalus Extract Mixture HT042 Improves Bone Growth, Mass, and Microarchitecture in Prepubertal Female Rats: A Microcomputed Tomographic Study

Table 3

Trabecular bone microarchitecture in the proximal tibial metaphysis.

Parameters (unit)ControlGH0.2% HT0420.6% HT042

BV/TV (%)19.018 ± 4.96124.001 ± 5.25722.973 ± 4.14524.053 ± 4.589
Tb.Th (mm)0.092 ± 0.0050.094 ± 0.0050.091 ± 0.0050.093 ± 0.004
Tb.N (mm−1)2.073 ± 0.5752.570 ±0.5752.535 ± 0.5232.581 ± 0.501
Tb.Sp (mm)0.705 ± 0.2110.543 ± 0.1190.544 ± 0.1280.560 ± 0.133
Tb.Pf (mm−1)10.847 ± 3.4917.936 ± 2.8738.224 ± 2.5237.413 ± 2.248
SMI1.833 ± 0.2641.638 ± 0.2371.623 ± 0.2121.602 ± 0.195

Values are expressed as the mean ± SD. and   versus control group. = 7-8 per group. BV/TV: bone volume per unit of total volume; Tb.Th: trabecular thickness; Tb.N: trabecular number; Tb.Sp: trabecular separation; Tb.Pf: trabecular bone pattern factor; SMI: structure model index.