Total Coumarins from<i> Hydrangea paniculata</i> Protect against Cisplatin-Induced Acute Kidney Damage in Mice by Suppressing Renal Inflammation and Apoptosis

<div>Effect of HP on infiltration of F4/80 positive macrophages and Ly6G-positive neutrophil in cisplatin-induced renal injury in mice. Eight to ten ×400 fields were counted and mean numbers of F4/80 positive and Ly6G positive inflammatory cells were compared at 72 hr after cisplatin administration. (a and b) Representative figures of F4/80 immunofluorescence microscopy and quantitative analysis. (c and d) Representative figures of Ly6G immunofluorescence microscopy and quantitative analysis. (e) Western blot analysis of F4/80 and Ly6G in kidney tissue homogenate. Data are expressed as mean ± SEM of three independent experiments.</div>

Evidence-Based Complementary and Alternative Medicine

fig6

Figure 6

Figure 6: Total Coumarins from<i> Hydrangea paniculata</i> Protect against Cisplatin-Induced Acute Kidney Damage in Mice by Suppressing Renal Inflammation and Apoptosis 

Figure 6 | Total Coumarins from Hydrangea paniculata Protect against Cisplatin-Induced Acute Kidney Damage in Mice by Suppressing Renal Inflammation and Apoptosis 