Manuka Honey Exerts Antioxidant and Anti-Inflammatory Activities That Promote Healing of Acetic Acid-Induced Gastric Ulcer in Rats

Figure 3

Effect of manuka honey on the gastric mucosal glycoprotein formation detected by PAS staining (PAS ×20). (a) SHAM showed high positive reaction in the surface mucous cells (black arrows). (b and c) Ulcer control group showed marked decrease (black arrows) or loss (dotted arrows) in PAS mucosal glycoprotein content of surface cells. (d) Positive control (ranitidine) showed marked preservation of mucopolysaccharides content of surface epithelium (arrows). (e) Manuka honey (0.6 gm/kg) showed moderate increase in PAS reacted glycoprotein. (f) Manuka honey (1.25 gm/kg) showed moderate increase in PAS reacted glycoprotein. (g) Manuka honey (2.5 gm/kg) showed marked increase in PAS reactive substance extending down along gastric glands (black arrows).