The Antidiabetic Activity of Nigella sativa and Propolis on Streptozotocin-Induced Diabetes and Diabetic Nephropathy in Male Rats

Table 5

Effect of treating diabetic rats with methanolic extracts of N. sativa and propolis for 4 weeks on water consumption.

Water consumed (mL/day)	Statistics	G1; N. control	G2; P. control	G3; N. sativa extract	G4; Propolis extract
1st week	Mean ± SE
	LSD
	0.05 = 3.257
	t-test	—	−4.56	7.40	4.01
2nd week	Mean ± SE
	LSD
	0.05 = 2.943
	t-test	—	−4.73	5.54	4.54
3rd week	Mean ± SE
	LSD
	0.05 = 3.725
	t-test	—	−8.00	7.88	19.00
4th week	Mean ± SE
	LSD
	0.05 = 4.453
	t-test	—	−1.58	0.63	1.00

Data are represented as mean ± SE. t-test values: : significant at and : significant at . ANOVA analysis: within each row, means with different superscript (a, b, c, or d) are significantly different at , whereas means with the same superscript letters mean that there is no significant difference at . LSD: least significant difference; NS: nonsignificant.