Therapeutic Effects of Fermented Flax Seed Oil on NC/Nga Mice with Atopic Dermatitis-Like Skin Lesions

Table 1

Image analysis of immunohistochemistry in FFSO-treated mice after AD elicitation.

Objective	Group
	CON	AE	AT
p-ERK 1/2	3,416 ± 63	44,068 ± 1013	17,601  ±
MMP9	639 ± 44	40,621 ± 813	8,329  ±
SP	1,367 ± 17	19,603 ± 655	3,934  ±
IL-4	1,767 ± 87	35,636 ± 910	10,304  ±
STAT6	251 ± 12	87,849 ± 1614	5,590  ±
NF-κB p65	846 ± 22	472,211 ± 715	5,954  ±
iNOS	803 ± 26	11,200 ± 745	8,323  ±
5-HT	886 ± 32	65,375 ± 740	9,584  ±
TNF-α	1,183 ± 162	30,737 ± 1462	10,449  ±
COX-2	1,251 ± 148	30,872 ± 1965	10,817  ±
FC receptor	3,095 ± 261	39,508 ± 1136	16,637  ±
LXR	132,645 ± 1920	2,704 ± 321	6,742  ±
PKC	994 ± 98	35,875 ± 2064	10,965  ±
IL-6	1,412 ± 260	45,001 ± 2763	20,590  ±
STAT3	973 ± 67	32,557 ± 1794	10,621  ±

(Image analysis for 10,000,000 particles/range of intensity: 80–100.)
p-ERK: phosphorylated-extracellular-signal-related kinase 1/2; MMP-9: matrix metalloproteinases-9; SP: substance-P; IL-4: interleukin 4; STAT6: signal transducers and activators of transcription 6; NF-κB p65: nuclear factor-κB p65; iNOS: inducible nitric oxide synthase; 5-HT: serotonin; TNF-α: tumor necrosis factor-; COX-2: cyclooxygenase 2; LXR: liver x receptor; PKC: protein kinase C; IL-6: interleukin 6; STAT3: signal transducers and activators of transcription 3; Ctrl: induced AD and given water; AE: induced AD and given water; AT: induced AD with FFSO treatment. compared with AE.