Research Article
Acyclic Sesquiterpenes from the Fruit Pericarp of Sapindus saponaria Induce Ultrastructural Alterations and Cell Death in Leishmania amazonensis
Figure 2
Scanning electron microscopy of promastigotes of L. amazonensis treated for 72 h with OGSA. (a) Untreated parasites have a typical elongated morphology. ((b) and (c)) Parasites treated with 100 μg/mL of OGSA show morphological changes as cell body deformation, twisting of the flagellum, and reticent increase in volume. ((d) to (f)) Parasites treated with 450 μg/mL OGSA exhibit more pronounced morphological changes. Scale bar = 1 μm.
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