Research Article

Acyclic Sesquiterpenes from the Fruit Pericarp of Sapindus saponaria Induce Ultrastructural Alterations and Cell Death in Leishmania amazonensis

Table 1

Cytotoxic and antiparasitic effect of S. saponaria L. on J774A1 macrophages and L. amazonensis forms, respectively.

S. saponaria
samples
Cytotoxicity
CC50 (μg/mL)
IC50 intracellular amastigotes (μg/mL)SI
intracellular amastigotes
IC50 promastigotes (μg/mL)

EHA0.45
OGSA7.35
SAP0.14