Research Article
Investigating the Mechanisms of Action of Depside Salt from Salvia miltiorrhiza Using Bioinformatic Analysis
Table 2
Top 10 nodes in the PPI network according to DC, BC, and CC scores.
| | DC | BC | CC | | Gene | Score | Gene | Score | Gene | Score |
| | JUN | 37 | CAT | 577.2475 | JUN | 0.186047 | | TNF | 34 | FOS | 309.3704 | TNF | 0.184438 | | NFKB1 | 34 | TNF | 256.2388 | NFKB1 | 0.184438 | | FOS | 33 | JUN | 251.4059 | FOS | 0.183908 | | IL6 | 33 | CCL2 | 205.0727 | IL6 | 0.183381 | | BCL2 | 31 | NFKB1 | 186.0261 | BCL2 | 0.181303 | | MAPK8 | 29 | IL6 | 185.3155 | MAPK8 | 0.181303 | | CREB1 | 28 | BCL2 | 166.0571 | CREB1 | 0.179775 | | NOS3 | 25 | CREB1 | 164.3064 | NOS3 | 0.178771 | | IL1B | 24 | CASP3 | 147.608 | IL1B | 0.178273 |
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PPI, protein-protein interaction; DC, degree centrality; BC, betweenness centrality; CC, closeness centrality.
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